ABO incompatible transplantation: to B or not to B.

نویسنده

  • Robert A Montgomery
چکیده

ABO antibodies (isoagglutinins) represent a formidable barrier to optimizing live donation and organ distribution. Blood group antigens are expressed on the endothelium of solid organs, and transplantation across a blood group barrier can result in hyperacute or acute antibody-mediated rejection (AMR). Based on blood group distributions in the United States, there is a 36% probability that any two individuals in the population will be ABO incompatible (ABOi), resulting in the exclusion of up to one third of willing live donors.

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عنوان ژورنال:
  • American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

دوره 4 7  شماره 

صفحات  -

تاریخ انتشار 2004